Scopolamine Powder CAS 51-34-3

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Scopolamine Powder CAS 51-34-3

Scopolamine is one of the most pharmacologically potent alkaloids in belladonna, which can be used to block parasympathetic nerves and to inhibit central nervous system.


Scopolamine hydrobromide is generally used in clinical, for anesthesia, analgesia, cough, antiasthmatic, effective for motion sickness, and stiffness and tremor control in Parkinson’s disease.

1. It inhibits salivary production more than atropine and reduces the heart rate.
2. It suppresses the cerebral cortex, causing drowsiness and forgetfulness.
3. The inhibitory effect of scopolamine on ocular smooth muscle and secretion of glands (salivary, bronchial, and sweat glands) is stronger than that of atropine.
4. Scopolamine is a peripheral anticholinergic drug.
5. Scopolamine can also block ganglion and nerve-muscle joints.
6. Relieve vasospasm and improve microcirculation.
7. The dilating pupil, regulating paralysis, and inhibiting secretion effect of scopolamine is 1 times stronger than atropine, but the duration is short.
8. Scopolamine appears to have a significant calming effect.
9. It has an obvious inhibitory effect on the center at the general therapeutic dose.
10. Hypnotic effects can be produced in large doses.

Chemical property:

Product nameScopolamine
CAS NO.51-34-3
Molecular formulaC17H21NO4
Molecular weight303.35
EINECS NO.200-090-3
Melting point59ºC
Specific rotationD20-28°(c=2.7)
Boiling point444.28°C
Refractive index1.5022
Storage conditionsAt a low temperature of -20°C, dry place with good ventilation.
solubilitySoluble in water(95g/L at 15ºC), freely soluble in ethanol(96%).
Acidity coefficient(pKa)7.55-7.81(at 25°C)


Clinically, it is mainly used for pre-anesthesia administration, and in the treatment of motion sickness, Parkinson’s disease, pregnancy vomiting, and radioactive vomiting.


Test Report:

AppearanceFine powderComplies
ColorWhite crystalline powderComplies
Particle Size100% pass 80 meshComplies
Loss on Drying5% Max4.06%
Part of UsedFlowerComplies
Chemical Control
Heavy metalsNMT 10ppmConforms
Arsenic (As)NMT 2ppmConforms
Mercury(Hg)NMT 2ppmConforms
Lead (Pb)NMT 2ppmConforms
GMO StatusGMO-FreeConforms
Pesticides ResiduesNMT 1ppmConforms


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