L-Glutathione CAS 70-18-8

Home » Products » L-Glutathione CAS 70-18-8

L-Glutathione CAS 70-18-8

Glutathione is a tripeptide compound formed by the condensation of glutamic acid, cysteine and glycine by peptide bonds. It is the most important low molecular mercaptan in mammalian cells to resist oxidative stress.


As nature’s antioxidant master, Glutathione’s appearance is colorless transparent slender granular crystal, which is soluble in water, dilute alcohol, liquid ammonia, dimethylformamide, but insoluble in ethanol and acetone. Widely found in bread yeast, wheat germ, animal liver, chicken blood, pig blood, tomato, pineapple, and cucumber.


It has the functions of anti-oxidation, free radical scavenging, detoxification, strengthening immunity, delaying senility, anti-cancer, and anti-radiation harm.
It also helps white blood cells kill bacteria, and prevents oxidation of vitamins C and E, preventing stroke and cataract formation.
In addition, glutathione has the function of binding to carcinogens and flinging them out of the body through urine.
Glutathione (GSH) plays a protective role in liver self-repair, synthesis, detoxification, estrogen inactivation, and other functions, and
is the primary antioxidant in the human body to counteract free radical damage.

Chemical property:

Product nameGlutathione
CAS NO.70-18-8
Molecular formulaC10H17N3O6S
Molecular weight307.32
EINECS NO.200-725-4
Melting point192-195°C(dec.)(lit.)
specific rotation-16.5º(c=2, H2O)
Boiling point754.5±60.0°C(Predicted)
Density1.4482(rough estimate)
Refractive index-17°(C=2, H2O)
Water Solubility50mg/mL
Acidity coefficient(pKa)pK12.12; pK23.53; pK38.66; pK49.12(at 25°C)
AppearanceWhite powder
PH Value3(10g/l,H2O,20°C)
StabilityStable. Incompatible with strong oxidizing agents.

L-Glutathione Content in plants:

Wheat germ98~107
Green peppers3~5
Sweet potato0.1~0.2
Kidney bean1~3
Mungbean sprout0.15~0.2

1. In the food industry: as food additives, such as help to reduce the time of making a break, food nutrients enrichment, as a stabilizer, prevent color burn in food, strengthen the flavor of meat and dry cheese products;
2. In biochemical research: for the detoxification caused by heavy metal, acrylonitrile, fluoride, carbon monoxide, and organic solvents;
3. In medical and health care area: Accelerate metabolism and reduce liver and kidney damage; Anti-allergy, anti-oxidation function;
4. Beauty products: Glutathione can enhance immunity, delay aging, anti-cancer, and anti-radiation harm.

1. Add modified enzyme into wheat germ;
2. Pulping evenly;
3. Filter the impurities;
4. Organic solvent extraction;
5. Separation;
6. Solvent removal;
7. Add protein precipitator to clarify;
8. Become protein;
9. HPLC separation;
10. Concentration;
11. Decoloration;
12. Spray dry;
13. End product of L-Glutathione.

Test Report:

Test ItemSpecificationResultAnalytical Method Reference
AppearanceWhite or almost white crystalline powderWhite crystalline powderVisual
Appearance of solution
(10% w/v in water)
Clear and colorlessCompliesVisual
Bulk Density≥0.50 g/ml0.52 g/mlIn-house
Tapped Density≥0.60 g/ml0.65 g/mlIn-house
Particle Size100% thru mesh 80CompliesMesh screen
IdentificationS.O.R.-15.5° ~ -17.5°-16.0°USP <781S>
InfraredPositivePositiveUSP <197K>
RelatedL-glutathione oxidized≤1.5%0.3%Glutathione USP monograph
Total impurities≤2.0%1.5%Glutathione USP monograph
Assay(dry basis)98.0% to 101.0%100.3%Glutathione USP monograph
Loss on drying(3 h at 105°C)≤0.5%0.3%USP <731>
Residue on Ignition≤0.1%<0.1%USP <281>
Ammonium≤200ppm<200ppmGlutathione USP monograph
Chloride≤200ppm<200ppmUSP <221>
Sulfate≤300ppm<300ppmUSP <221>
Iron≤10ppm<10ppmUSP <241>
Heavy metals≤10ppm<10ppmUSP <231>Method I
Total Plate Count≤1000 cfu/g<10 cfu/gUSP <61>
Yeast and Mold≤100 cfu/g25 cfu/gUSP <61>
Coliforms≤30 cfu/g<10 cfu/gUSP <61>
E. ColiNegative/gNegativeUSP <62>
SalmonellaNegative/10gNegativeUSP <62>
Staphylococcus AureusNegative/gNegativeUSP <62>


Enter your email address to receive all news, updates on new arrivals,
special offers and other discount information.

    Go to Top