Kojic Acid Dipalmitate, KAD, CAS 79725-98-7

Description

Kojic acid dipalmitate is an improved derivative of kojic acid, which overcomes the instability of kojic acid to light, heat and metal ions, and maintains the effect of inhibiting tyrosinase activity and blocking melanin formation of the skin.

Functions:
1. Skin whitening;
2. Helps absorption of cosmetics to the skin;
3. Has antibacterial, antifungal, and antioxidant attributes.

Chemical property:

Product name	Kojic acid dipalmitate
CAS NO.	79725-98-7
Molecular formula	C38H66O6
Molecular weight	618.93
EINECS NO.	207-922-4
Melting point	92-96°C
Boiling point	684.7±55.0°C
Density	0.99±0.1 g/cm3
Solubility	Soluble in ware alcohol, mineral oil, and esters.
Stability	Light and heat stability; PH Stability 4-9; color stability

Application:
1. In cosmetics: whitening, anti-oxidant, improves healing and helps absorption;
2. In Agriculture: as pesticides;
3. In Medicine: cephalosporin-type antibiotics;
4. In Food: as preservative, color stabilizer or food aromatizer in food processing area;
5. In other fields: as an iron analytical reagent and film spotting agent, etc;

Production:

Test Report:

Items	Standards	Results
Physical Analysis
Description	Off-White to White Crystalline	Complies
Assay	99%	99.22%
Mesh Size	100 % pass 80 mesh	Complies
Ash	≤ 5.0%	2.85%
Loss on Drying	≤ 5.0%	2.85%
Chemical Analysis
Heavy Metal	≤ 10.0 mg/kg	Complies
Pb	≤ 2.0 mg/kg	Complies
As	≤ 1.0 mg/kg	Complies
Hg	≤ 0.1 mg/kg	Complies
Microbiological Analysis
Residue of Pesticide	Negative	Negative
Total Plate Count	≤ 1000cfu/g	Complies
Yeast&Mold	≤ 100cfu/g	Complies
E.coil	Negative	Negative
Salmonella	Negative	Negative

Reference formula:

Application Area	products	Dosage
cosmetic	Toner, lotion, cream, essence, etc.	1%-3%
1.Kojic acid dipalmitate mask reference formula:
Ingredient	Proportion(%)	Ingredient	Proportion (%)
Kojic acid dipalmitate	0.3	Silk fibroin	3
Ethanol	3	Polyacrylic acid	1
Methylparaben	0.1	Propolis	3
Squalane	2	Propylene Glycol	5
Zinc oxide	10	Kaolin	10
Spices	Right amount
2.Kojic acid dipalmitate lotion reference formula:
Ingredient	Proportion(%)	Ingredient	Proportion (%)
Kojic acid dipalmitate	0.15	Placental fluid	8
Glycerin	5	Polyethylene glycol	2
Oil-based polyoxyethylene ether	2	Ethanol	10
Potassium hydroxide	0.03	Spices	Right amount
Preservative	Right amount	Refined water	Increase to 100
3.Kojic acid dipalmitate Cream reference formula A:
Ingredient	Proportion(%)	Ingredient	Proportion (%)
Atractylodes	5~10	White tuckahoe	5~10
Ampelopsis	5~10	Angelica	5~10
Bletilla striata	5~10
3.Kojic acid dipalmitate Cream reference formula B:
Glycerin	3~8	Tea polyphenols	1~3
Vitamin A	1~2	SOD	0.3-0.7
Kojic acid dipalmitate	0.5-2
3.Kojic acid dipalmitate Cream reference formula C:
Vaseline	20~40	Distilled water	10~15
Water	50-250