Hyaluronic Acid, Cosmetic Grade Acid Hyaluronic, CAS 9004-61-9

Description

Introduction:

Product name:Hyaluronic Acid Powder
Other name: sodium hyaluronate
CAS: 9004-61-9
Molecular Formula:C14H22NNaO11
Sodium hyaluronate:≥92%
Appearance: White powder
Grade:Cosmetic grade, Food grade, Eye-drop grade
We are specialized in this product and can provide you below molecular weight:

<10000 dalton
10000 dalton
15,000-50,000 dalton
50,000-200,000 dalton
200,000-1.4 million dalton
1.4million-1.6million dalton
1.8million-2 million dalton
>2 million dalton

Hyaluronic Acid can also be used to treat osteoarthritis of the knee. They are administered as a course of injections into the knee joint, which are believed to supplement the viscosity of the joint fluid, thereby lubricating the joint, cushioning the
joint, and producing an analgesic effect.
Hyaluronic Acid has also been used in the synthesis of biological scaffolds for woundhealing applications. These scaffolds typically have proteins such as fibronectin attached to the Hyaluronic Acid to facilitate cell migration into the wound.
Hyaluronic Acid is also used in antiadhesive products, which are widely used in pelvic and abdominal surgery to prevent
postoperative adhesions.

Function

1.Hyaluronic acid is a substance that is naturally present in the human body. It is found in the highest concentrations in fluids in the eyes and joints.
2.The hyaluronic acid that is used as medicine is extracted from rooster combs or made by bacteria in the laboratory.
3.Hyaluronic acid is also used as a lip filler in plastic surgery.It is also using to prevent the effects of aging.
4.Hyaluronic Acid (HA, Hyaluronic, Cyclic Acid) is a critical component of the skin that helps to retain moisture, keeping the skin firm, and preventing wrinkles by adding volume to the skin.

Grade	Type	Molecular Weight	Function
Cosmetic Grade	High molecular weight	1800-2000kDa	Excellent moisturizing and lubricating property; excellent sunscreen repair
		2000-2200kDa
		2200-2500kDa
	Intermediate molecular weight	80-100kDa	Excellent moisturizing property, slow-release, and stable emulsification
		120-150kDa
	Low molecular weight	20-40kDa	Long-lasting moisturizing and wrinkle-resistant cosmetology
	Oligo molecular weight	≤10kDa	Deep absorption and nourishment of skin
Food Grade	Intermediate molecular weight	100-200kDa	Anti-aging; reduce inflammation; lubricate joints; reduce pain and wrinkle.
		200-400kDa
		400-600kDa

Application:

1. Food Industry
We recommand Food Grade with the Molecular Weight 800,000Da-1,200,000Da. It can be added into drinks, mink products, health care capsules, etc.

2. Cosmetic Industry
(1) <10,000Da (Super Low Molecular Weight):
Making hyaluronic acid smaller means it can reach a bit farther into skin’s uppermost layers for visibly enhanced results, so it has the best effect of moisturzing and anti-aging.
(2) 10,000Da-200,000Da (Low Molecular Weight)
It has better moisture effect than regular molecular weight.
(3) 200,000Da-1,600,000Da (Regular Molecular Weight)
It can retain moisture, keep the skin firm, and prevent wrinkles by adding volume to the skin.
(4) >1,600,000Da (High Molecular Weight)
It can keep moisturing for longer time, and repair skins.

3. Eyedrop Industry
We recommand Eyedrop Grade for you. It can be used in eye surgeries including cataract removal, corneal transplantation, and repair of a detached retina and other eye injuries.

4. Injection Industry
We recommand Injection Grade for you. It can be made into HA filler used on our body, like face, lip, breast, etc.

Test :

ITEM	STANDARD	ITEM	STANDARD
Appearance	White powder	Molecular weight	(0.8-1.2)*106
Identify	Infrared absorption	Bulk density	0.2-0.5g/cm3
Glucuronic acid	Glucuronic acid	Protein	≤0.1%
Sodium hyaluronate	95.0-105.0%	Chlorides	≤0.5%
PH(0.5% aq. sol., 25℃)	5.0~8.5	ash content	<13%
Absorbance(0.5% aq. sol., 25℃)	A280nm≤0.25	Residue on ignition	≤20.0%
Appearance of Solution	T550nm≥99.0%	Heavy metal (as Pb)	≤20mg/kg
Loss on drying	≤10.0%	Iron	≤2mg/kg
Intrinsic viscosity	16.6-17.7 dL/g	Arsenic	≤2mg/kg
Bacteria counts	≤100cfu/g	Staphylococcus aureus	Negative/g
Molds & Yeasts	≤10cfu/g	Salmonella	Negative/g
Hemolysis	Negative/g	Escherichia coli	Negative/g
Viable Hemolytical Streptococci	Negative/g	Conclusion:	Up to the EP9.0 standards