Dextromethorphan Hydrobromide Powder CAS 125-69-9

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Dextromethorphan Hydrobromide Powder CAS 125-69-9

Dexmethorphan hydrobromide, is an engineered morphine reorganized by a Swiss company in 1950 for treatment of dry coughs, including cough caused by upper respiratory tract infections (such as colds and pharyngitis) and bronchitis.




  1. To treat a dry (nonproductive) cough caused by colds, flu or inhaled irritants.
  2. The most popular cold and cough medications.
  3. Help treat pain and a variety of other disturbances as well when added in other preparations.

Chemical property:

Product nameDextromethorphan hydrobromide monohydrate
AppearanceWhite Crystal Powder
CAS NO.125-69-9
Molecular formulaC18H25NO
EINECS No.204-750-1
Molecular weight271.4
Melting point123-127°C
Specific rotation+28~+30°(c=1.85, H2O)
Flash Point11°C
Storage conditionStore at RT.
SolubilitySparingly soluble in water, freely soluble in ethanol(96%).
PH ValuepH (10g/l, 25°C): 5.2~6.5


  1. Dextromethorphan Capsules
  2. Dextromethorphan Chewable Tablets
  3. Dextromethorphan Extended-Release Suspension
  4. Dextromethorphan Liquid and Syrup
  5. Dextromethorphan Lozenges
  6. Dextromethorphan Orally Disintegrating Strips


Test Report:

Test ItemsSpecificationResult
AppearanceWhite  Crystalline PowderComplies
Loss on Drying≤0.5%0.08%
Ignttion Residue≤0.1%0.03%
Related ImpuritiesIndividual impurity ≤ 0.2%0.10%
Total  impurities ≤0.5%0.32%
Assay(by HPLC)98.5 ~ 100.5 %99.60%
Heavy MetalsPb≤3.00ppm;
Hg should not be detected.
Not detected
Total bacterial count10000cfu/g max.Complies
Total molds count300cfu/g max.Complies
Staphylococcus aureusShould not be detected.Not detected.
SalmonellaShould not be detected.Not detected.
E.coliShould not be detected.Not detected.
ConclusionThis batch complies with company standard.


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