Curcumin also has anti-cancer and inhibitory effects on the generation, proliferation, and metastasis of tumor cells, which can also prevent the occurrence of experimental fatty liver.
Curcumin CAS 458-37-7
Description
Curcumin is a natural phenolic antioxidant extracted from the roots of turmeric, zedoary, mustard, curry, turmeric, or other turmeric plants. It is commonly used as a food coloring. Curcumin is non-toxic and has many pharmacological effects, such as choleric, anti-infection, paralytic contraction of the uterus, lowering blood cholesterol, antiviral, antibacterial, antioxidant (stronger than α-tocopherol), anticoagulant, lowering blood lipid, and anti-atherosclerosis.
Chemical property:
| Product name | Curcumin |
| CAS NO. | 458-37-7 |
| Molecular formula | C21H20O6 |
| Molecular weight | 368.38 |
| EINECS NO. | 207-280-5 |
| Melting point | 183°C |
| Boiling point | 418.73°C |
| Density | 0.93 |
| Refractive index | 1.4155-1.4175 |
| Flash point | 208.9±23.6°C |
| Storage temperature | −20°C |
| Appearance | Odorless orange powder |
| Acidity coefficient(pKa) | 8.09(at 25°C) |
| pH Value | Yellow (7.8)to red-brown(9.2) |
| Ethanol solubility | 10mg/mL |
| Water solubility | Slightly soluble in hot water |
| Stability | Stable, but may be light sensitive. Incompatible with strong oxidizing agents. |
Application:
1. Used as food or beverages colorants;
2. Application in pH test pape;
3. Phamaceuticals: has antioxidant, anti-tumor, anti-inflammatory and anti-cancer effect.
Production:
Turmeric powder→immersion extraction→filtration→immersion extraction
↓
ethanol dissolution← filtration←static stratification←concentration
↓
extraction→distillation→secondary distillation
Test Report:
| Analysis | Specification | Result | Test method |
| Physical Description | |||
| Appearance | Yellow fine powder | Complies | Visual |
| Odor | Characteristic | Complies | Organoleptic |
| Tasted | Characteristic | Complies | Organoleptic |
| Particle size | 100% through 80 mesh | Complies | 80 Mesh |
| Extract solvent | Water | Complies | / |
| Bulk density | 40~65g/100ml | 45.8g/100ml | / |
| Chemical Tests | |||
| Assay (curcumin) | 95.00% | HPLC | HPLC |
| Loss on Drying | 5.0% Max | 4.72% | 5g/105°C/2hrs |
| Sulphated Ash | 5.0%Max | 3.90% | 2g/525°C/3hrs |
| Heavy metals | |||
| Pb | 2ppm Max | Complies | AAS |
| As | 2ppm Max | Complies | AAS |
| Cd | 1ppm Max | Complies | AAS |
| Hg | 1ppm Max | Complies | AAS |
| Microbiology Control | |||
| Total plate count | 10,000cfu/g Max | Complies | AOAC |
| Yeast & Mold | 1000cfu/g Max | Complies | AOAC |
| E. Coli | Negative | Negative | AOAC |
| Salmonella | Negative | Negative | AOAC |
| Conclusion | Complies with the standards. | ||
| General Status | Non-GMO, Non-irradiation. | ||
| Packing and Storage | |||
| Packing: Pack in paper-carton and two plastic bags inside. | |||
| Shelf life: 2 years when properly stored. | |||
| Storage: Store in a well-closed place with constant low temperature and no direct sunlight. | |||
Packaging
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