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Alpha GPC CAS 8319-77-9

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Alpha GPC CAS 8319-77-9

Glycerol phosphate choline (GPC) is a naturally occurring phospholipid metabolic intermediate found in cells throughout the human body.

Description

Introduction:

GPC is composed of choline, glycerol, and phosphoric acid. Glycerol phosphate choline (GPC) is a major preservation form of choline and is recognized as the source of choline. Choline produced by GPC is a water-soluble B vitamin that plays an important role in the production of certain hormones and neurotransmitters, such as acetylcholine and human growth hormone, and thus plays an important role in the brain and nervous system.

Functions:

  1. Protect the metabolism of choline, ensure the synthesis of acetylcholine and lecithin in the neuronal membrane, improve blood circulation;
  2. Improved cognitive, memory, and behavioral responses in patients with brain capillary nerve trauma;
  3. Improve the behavioral and emotional disorders caused by brain decline.
  4. Potential of treatment and prevention of various biochemical diseases;
  5. Relieve body tension;
  6. Improve memory, thinking skills, and learning.

Chemical property:

Product nameCholine glycerophosphate/ α-GPC
CAS NO.28319-77-9
Molecular formulaC8H20NO6P
Molecular weight257.22
EINECS NO.248-962-2
Melting point142.5-143°
Specific rotation D25 -2.7° (c = 2.7 in water, pH 2.5); D25 -2.8° (c = 2.6 in water, pH 5.8)
Flash point11 °C
AppearanceWhite to off white powder
Storage condition −20°C
SolubilityMiscible with water; soluble in methanol, ethanol, insoluble in chloroform, ether, oil, etc., and has no characteristic absorption under ultraviolet and visible light.

Application:

  1. Pharmaceutical: as digestive system drugs, adjuvant drugs for liver disease, Alzheimer s disease, dementia, stroke, and “mini-stroke”.
  2. Dietary supplement: to improve memory, thinking skills, and learning;

Production:

Test Report:

ItemSpecificationResult
AppearanceWhite crystalline powderComplies
Related substance (HPLC)Total impurity ≤0.5%0.20%
Max single impurity ≤0.1%0.06%
OdorCharacteristicComplies
Assay99%99.80%
Sieve analysis100% pass 80 meshComplies
Loss on Drying≤1.0%0.12%
Residue on Ignition≤1.0%0.09%
Heavy Metal<10ppmComplies
As<0.1ppm0.05ppm
Pb<0.1ppm0.05ppm
Cd<0.1ppm0.05ppm
Residual Solvents<100ppmComplies
Residual PesticideNegativeComplies
Microbiology
Total Plate Count<1000cfu/gComplies
Yeast & Mold<100cfu/gComplies
E.ColiNegativeComplies
SalmonellaNegativeComplies

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